Well, this happened… and so far it’s seamless, though very experimental.
Using the dev channel of Windows 10 with WSLg (WSL 2 with the graphical update) and WSL Ubuntu 20.04. I installed the .deb, a few package dependencies, and explicitly added the Nyxt icon to the Start menu. Windows itself is running in a virtual machine, as the Windows 10 dev branch is not stable. I look forward to doing more Nyxt on Windows 10, as WSLg it comes out of dev, into beta, and release later this year as part of the Windows 10 Sun Valley update.
Once WSLg was running, the commands I used were:
wget 'https://github.com/atlas-engineer/nyxt/releases/download/2.0.0/nyxt-ubuntu.zip' unzip nyxt-ubuntu.zip sudo apt install libfixposix-dev libwebkit2gtk-4.0-dev xclip enchant libfixposix3 sudo apt --fix-broken install sudo dpkg -i nyxt_2.0.0_amd64.deb nyxt